The Arizona Diamondbacks versus the Milwaukee Brewers is one of many strong options on today’s MLB slate.

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MLB Betting Info Today – Sept. 21

Pittsburgh Pirates (72-82) at Cincinnati Reds (75-80)

Betting Info & Picks

• Moneyline Favorite: Reds -125
• Moneyline Underdog: Pirates +105
• Total: 8.5 Runs (-115 to go over, -105 to go under)
• Prediction: Reds 6, Pirates 5
• Moneyline Pick: Reds (-125) over the Pirates (+105)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: SportsNet PT
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 1:10 PM ET
• Venue: Great American Ball Park
• Location: Cincinnati, Ohio
• Reds Starter: Rhett Lowder (1-2, 1.74 ERA)
• Pirates Starter: Jared Jones (6-7, 3.85 ERA)

Washington Nationals (68-86) at Chicago Cubs (79-75)

Betting Info & Picks

• Moneyline Favorite: Cubs -145
• Moneyline Underdog: Nationals +120
• Total: Runs ( to go over, to go under)
• Prediction: Cubs 6, Nationals 4
• Moneyline Pick: Cubs (-145) over the Nationals (+120)

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How to Watch

• TV Channel: MASN2
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 2:20 PM ET
• Venue: Wrigley Field
• Location: Chicago, Illinois
• Cubs Starter: Kyle Hendricks (4-11, 6.25 ERA)
• Nationals Starter: MacKenzie Gore (9-12, 4.17 ERA)

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Detroit Tigers (80-74) at Baltimore Orioles (86-68)

Betting Info & Picks

• Moneyline Favorite: Orioles -120
• Moneyline Underdog: Tigers +100
• Total: 8.5 Runs (-105 to go over, -115 to go under)
• Prediction: Orioles 6, Tigers 5
• Moneyline Pick: Orioles (-120) over the Tigers (+100)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: BSDET
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:05 PM ET
• Venue: Oriole Park at Camden Yards
• Location: Baltimore, Maryland
• Orioles Starter: Cade Povich (2-9, 5.74 ERA)
• Tigers Starter: Reese Olson (4-8, 3.5 ERA)

Minnesota Twins (81-73) at Boston Red Sox (76-78)

Betting Info & Picks

• Moneyline Favorite: Red Sox -130
• Moneyline Underdog: Twins +110
• Total: 8 Runs (-110 to go over, -110 to go under)
• Prediction: Red Sox 6, Twins 5
• Moneyline Pick: Red Sox (110) over the Twins (-130)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: Fenway Park
• Location: Boston, Massachusetts
• Red Sox Starter: Kutter Crawford (8-15, 4.19 ERA)
• Twins Starter: Pablo Lopez (15-8, 3.84 ERA)

Toronto Blue Jays (73-81) at Tampa Bay Rays (76-78)

Betting Info & Picks

• Moneyline Favorite: Rays -135
• Moneyline Underdog: Blue Jays +115
• Total: 8 Runs (+100 to go over, -120 to go under)
• Prediction: Rays 5, Blue Jays 4
• Moneyline Pick: Rays (-135) over the Blue Jays (+115)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSSUN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: Tropicana Field
• Location: St. Petersburg, Florida
• Rays Starter: Taj Bradley (6-11, 4.39 ERA)
• Blue Jays Starter: Yariel Rodriguez (1-6, 4.29 ERA)

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Philadelphia Phillies (92-62) at New York Mets (85-69)

Betting Info & Picks

• Moneyline Favorite: Mets -115
• Moneyline Underdog: Phillies -105
• Total: 7.5 Runs (+100 to go over, -120 to go under)
• Prediction: Mets 5, Phillies 4
• Moneyline Pick: Mets (-115) over the Phillies (-105)
• Total Pick: Over 7.5 Runs

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How to Watch

• TV Channel: SNY
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: Citi Field
• Location: Queens, New York
• Mets Starter: Sean Manaea (11-5, 3.26 ERA)
• Phillies Starter: Ranger Suárez (12-7, 3.13 ERA)

Atlanta Braves (83-71) at Miami Marlins (57-97)

Betting Info & Picks

• Moneyline Favorite: Braves -250
• Moneyline Underdog: Marlins +200
• Total: 8 Runs (+100 to go over, -120 to go under)
• Prediction: Braves 5, Marlins 4
• Moneyline Pick: Braves (-250) over the Marlins (+200)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSFL
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 4:10 PM ET
• Venue: LoanDepot park
• Location: Miami, Florida
• Marlins Starter: Adam Oller (1-4, 5.4 ERA)
• Braves Starter: Max Fried (9-10, 3.49 ERA)

San Francisco Giants (75-79) at Kansas City Royals (82-72)

Betting Info & Picks

• Moneyline Favorite: Royals -150
• Moneyline Underdog: Giants +125
• Total: 8.5 Runs (-110 to go over, -110 to go under)
• Prediction: Royals 5, Giants 4
• Moneyline Pick: Royals (-150) over the Giants (+125)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: BSKC
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 5:10 PM ET
• Venue: Kauffman Stadium
• Location: Kansas City, Missouri
• Royals Starter: Brady Singer (9-11, 3.53 ERA)
• Giants Starter: Landen Roupp (0-1, 3.02 ERA)

Seattle Mariners (79-75) at Texas Rangers (73-81)

Betting Info & Picks

• Moneyline Favorite: Rangers -145
• Moneyline Underdog: Mariners +120
• Total: 8 Runs (+100 to go over, -120 to go under)
• Prediction: Rangers 5, Mariners 4
• Moneyline Pick: Rangers (-145) over the Mariners (+120)
• Total Pick: Under 8 Runs

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How to Watch

• TV Channel: ROOT Sports NW
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 7:05 PM ET
• Venue: Globe Life Field
• Location: Arlington, Texas
• Rangers Starter: Max Scherzer (2-4, 3.95 ERA)
• Mariners Starter: Emerson Hancock (3-4, 4.83 ERA)

Arizona Diamondbacks (86-68) at Milwaukee Brewers (88-66)

Betting Info & Picks

• Moneyline Favorite: Brewers -115
• Moneyline Underdog: Diamondbacks -105
• Total: 8.5 Runs (+100 to go over, -120 to go under)
• Prediction: Brewers 5, Diamondbacks 4
• Moneyline Pick: Brewers (-115) over the Diamondbacks (-105)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: ARID
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 7:10 PM ET
• Venue: American Family Field
• Location: Milwaukee, Wisconsin
• Brewers Starter: Aaron Civale (7-8, 4.48 ERA)
• Diamondbacks Starter: Merrill Kelly (4-0, 4 ERA)

Los Angeles Angels (62-92) at Houston Astros (84-70)

Betting Info & Picks

• Moneyline Favorite: Astros -250
• Moneyline Underdog: Angels +200
• Total: 8 Runs (-105 to go over, -115 to go under)
• Prediction: Astros 5, Angels 3
• Moneyline Pick: Astros (-250) over the Angels (+200)
• Total Pick: Under 8 Runs

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How to Watch

• TV Channel: SCHN
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 7:10 PM ET
• Venue: Minute Maid Park
• Location: Houston, Texas
• Astros Starter: Ronel Blanco (11-6, 2.88 ERA)
• Angels Starter: Reid Detmers (4-7, 6.05 ERA)

Cleveland Guardians (90-65) at St. Louis Cardinals (77-77)

Betting Info & Picks

• Moneyline Favorite: Cardinals -135
• Moneyline Underdog: Guardians +115
• Total: 8 Runs (-115 to go over, -105 to go under)
• Prediction: Cardinals 5, Guardians 4
• Moneyline Pick: Cardinals (115) over the Guardians (-135)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: BSGL
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 7:15 PM ET
• Venue: Busch Stadium
• Location: St. Louis, Missouri
• Cardinals Starter: Miles Mikolas (8-11, 5.49 ERA)
• Guardians Starter: Matthew Boyd (2-1, 2.52 ERA)

Chicago White Sox (36-117) at San Diego Padres (87-66)

Betting Info & Picks

• Moneyline Favorite: Padres -275
• Moneyline Underdog: White Sox +225
• Total: 8 Runs (-120 to go over, +100 to go under)
• Prediction: Padres 6, White Sox 3
• Moneyline Pick: Padres (-275) over the White Sox (+225)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: NBCS-CHI
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 8:40 PM ET
• Venue: PETCO Park
• Location: San Diego, California
• Padres Starter: Martín Pérez (4-5, 4.36 ERA)
• White Sox Starter: Chris Flexen (2-14, 5.09 ERA)

New York Yankees (89-64) at Oakland Athletics (67-86)

Betting Info & Picks

• Moneyline Favorite: Yankees -185
• Moneyline Underdog: Athletics +150
• Total: 8 Runs (+100 to go over, -120 to go under)
• Prediction: Yankees 5, Athletics 4
• Moneyline Pick: Yankees (-185) over the Athletics (+150)
• Total Pick: Over 8 Runs

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How to Watch

• TV Channel: YES
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 9:07 PM ET
• Venue: Oakland-Alameda County Coliseum
• Location: Oakland, California
• Athletics Starter: JP Sears (11-11, 4.24 ERA)
• Yankees Starter: Carlos Rodón (15-9, 4.12 ERA)

Colorado Rockies (59-94) at Los Angeles Dodgers (91-62)

Betting Info & Picks

• Moneyline Favorite: Dodgers -275
• Moneyline Underdog: Rockies +225
• Total: 8.5 Runs (-115 to go over, -105 to go under)
• Prediction: Dodgers 5, Rockies 4
• Moneyline Pick: Dodgers (-275) over the Rockies (+225)
• Total Pick: Over 8.5 Runs

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How to Watch

• TV Channel: SportsNet LA
• Live Stream: Watch on Fubo (Regional restrictions may apply)
• Game Time: 9:10 PM ET
• Venue: Dodger Stadium
• Location: Los Angeles, California
• Dodgers Starter: Walker Buehler (1-5, 5.54 ERA)
• Rockies Starter: Cal Quantrill (8-10, 4.68 ERA)

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